Thunder God Vine - Effective Herbal Cancer Treatment

An ancient Chinese herb that has long played a crucial role in traditional Chinese medicine has been found to eradicate tumors in mice with pancreatic cancer. According to a research done by University of Minnesota’s Masonic Tripterygium wilfordii (otherwise known as 'thunder god vine’ or lei gong teng) possesses a unique compound capable of fully eradicating cancer tumors within 40 days — even after discontinuing the treatment. The study was published in the journal Science Translational Medicine and funded by the National Institutes of Health.

Ashok Saluja (study leader and vice chairman of research at the Cancer Center) explained to Bloomberg, "This [herb] is just unbelievably potent in killing tumor cells. You could see that every day you looked at those mice, the tumor was decreasing and decreasing, and then just gone."

The herb is known to contain something called triptolide which is thought to be the key component that may be responsible for the anti-tumor capabilities. Triptolide is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities. Its molecular mechanism of action, however, has remained largely elusive to date. We report that triptolide covalently binds to human XPB (also known as ERCC3), a subunit of the transcription factor TFIIH, and inhibits its DNA-dependent ATPase activity, which leads to the inhibition of RNA polymerase II–mediated transcription and likely nucleotide excision repair. The identification of XPB as the target of triptolide accounts for the majority of the known biological activities of triptolide. These findings also suggest that triptolide can serve as a new molecular probe for studying transcription and, potentially, as a new type of anticancer agent through inhibition of the ATPase activity of XPB.

Thunder god vine's clinical use is restricted due to its scarce water solubility and some toxic effects. The team was able to effectively isolate this triptolide and convert it into a water soluble form with minimum toxicity, which researchers then injected into the mice regularly for a little more than one month, which was enough to cure the animals' cancers.

Triptolide from this herb has been identified as a cancer fighting agent for a broad range of solid tumors and has shown to be effective on the treatment of multiple cancer types in many previous researches also:

2011 - In a report published in the March issue of Nature Chemical Biology, researchers at the Johns Hopkins School of Medicine had discovered that triptolide works by blocking gene control machinery in the cell.

2007 - Researchers from both Yale University and Columbia University found that triptolide effectively triggers cancer cell apoptosis, also known as programmed cell death in polycystic kidney disease (PKD).

2006 - Researchers from the University of Texas MD Anderson Cancer Center in a study found that triptolide targets various leukemic cancer cell lines, as well as increases the effectiveness of other anticancer agents.

Thunder god vine has been used in traditional Chinese medicine for conditions involving inflammation or overactivity of the immune system and is taken for excessive menstrual periods or autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, Crohn's disease and lupus. It is also used for abscesses, boils, fever, inflammation, psoriasis and as a male contraceptive.

Use of thunder god vine may cause a number of adverse effects, including diarrhea, upset stomach, hair loss, headache, menstrual changes & skin rash. Taking the herb for five years or longer has also been found to decrease bone mineral density in women.

Always Consult a Naturopath Doctor Before Starting a Herbal Treatment